Chorea disclosing a polycythemia vera
نویسندگان
چکیده
منابع مشابه
Chorea disclosing a polycythemia vera
Chorea is a rare complication of polycythemia. We report the case of a 70 year-old woman whose polycythemia vera (PV), with Janus Kinase-2 (JAK2) mutation, presented as chorea. Chorea resolved quickly after hydroxyurea therapy.
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Polycythemia vera (PV) is a clonal stem cell disorder characterized by increased erythrocyte production. Its etiology is not fully understood, and hemorrhage, thrombosis, and hyperviscosity may occur at any time during the course of this disorder. Treatment depends on the most affected cell type, duration and severity of the condition, and patient age. PV treatment can involve phlebotomy, admin...
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Chorea is a hyperkinetic movement disorder characterized by excessive spontaneous movements that are irregularly timed, randomly distributed and abrupt. Chorea in an elderly patient poses a diagnostic challenge. The differential diagnosis is broad and includes medication effects, vascular disorders, metabolic abnormalities, autoimmune syndromes and neurodegenerative disorders.1,2 Important caus...
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BACKGROUND AND OBJECTIVE Current guidelines for the management of patients with polycythemia vera (PV) derive from a few clinical trials and several uncontrolled clinical studies. The purpose of this paper is to critically review the available evidence in literature for selecting the best treatment in the single patient. METHODS The authors have been working in this field contributing origina...
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BACKGROUND AND OBJECTIVE Polycythemia vera (PV) is an acquired clonal myeloproliferative disorder characterized by increased production of mature red cells. We still lack a molecular target responsible for this disorder; however, recent investigations have focused on a number of molecules involved in signal transduction pathways mediated by erythropoietin (Epo) and other growth factors. Here we...
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ژورنال
عنوان ژورنال: Neuropsychiatric Disease and Treatment
سال: 2014
ISSN: 1176-6328
DOI: 10.2147/ndt.s60694